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Jennifer Aniston and Chelsea Handler have become such close friends that Chelsea has taken it upon herself to fight Jen’s battles for her. The main target? Brad Pitt‘s partner Angelina Jolie.

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Chelsea and Jen are such good friends that they spent Thanksgiving together in Mexico this year.

They may just be her own personal feelings, but Chelsea has a strong opinion about Angelina and she unleashed them during her show in Newark, N.J. on Friday night.

The comedian called Angie a home-wrecking “b****” and then shared her thoughts on why Angie says she has no female friends (in not so nice of terms).

OK! NEWS: CHELSEA HANDLER TALKS HER BIKINI-CLAD THANKSGIVING WITH JENNIFER ANISTON

After yelling at a disruptive audience member, Chelsea began making fun of Angie.

“She’s a home wrecker, she is,” Chelsea said. “She can rescue as many babies from as many countries as she wants to. I don’t f***ing believe you.”

And those are only the least offensive things Chelsea had to say!

**WARNING: THE VIDEO BELOW CONTAINS EXPLICIT LANGUAGE!**

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