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The animated flick Rango scored the No. 1 spot at the box office this weekend, with a $38 million opening. The film stars Johnny Depp as a humorous chameleon who takes on the position of sheriff in a desert town.

Johnny teamed up with Pirates of the Caribbean director Gore Verbinski for the flick which also stars Isla Fisher, Timothy Olyphant, and Abigail Breslin.

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Catch the other movies who rounded out the Top 5 in the list below, via MTV NEWS.

2. The Adjustment Bureau: The action romance starring Matt Damon and Emily Blunt debuted at the box office with $20.9 million.

3. Beastly: Most probably a teen favorite, the Beauty and the Beast starring Vanessa Hudgens and Alex Pettyfer raked in $10.1 million opening.

4. Hall Pass: The Farrelly brothers-directed flick brought in $9 million its second week of release and earned a total of $27 million since it hit theaters.

OK! GALLERY: ALYSSA MILANO DEBUTS GROWING BABY BUMP AT HALL PASS PREMIERE

5. Gnomeo and Juliet: The animated flick topped the box office last week, and rounded out the Top 5 this week, earning $6.9 million. With executive producer by Elton John — whose music is played throughout the film — this retelling of Shakespeare’s Romeo and Juliet stars James McAvoy and Emily Blunt as the leading gnomes.

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