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Jesse James‘ first alleged mistress to surface, Michelle “Bombshell” McGee, messed with the wrong comedian — E! late night queen Chelsea Handler. Chelsea took the first jab at McGee, reacting to the number of tattoos on the former model.

“I guess she doesn’t read magazines which makes sense, since she basically has one on her face,”Chelsea joked via Entertainment Weekly‘s Pop Watch, a quip that is pretty harmless for the comedian, who has a reputation of being vicious with her words.

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McGee reacted harshly to Chelsea’s comment on her Facebook page.

“Chelsea, here’s some free advice: Use some of that Botox from your forehead and put it in your flabby underarm skin. I’ve seen better wings in a bucket of KFC chicken.”

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Chelsea, never one to be undermined, reacted to McGee’s retort with some attitude.

She started out her comeback repeating the chicken wing line and wagging her underarms, joking she would dip them in blue cheese.

OK! EXCLUSIVE: CHELSEA HANDLER’S FAVORITE THINGS

The comedian’s good humor didn’t last long — she lost her cool midway through her tirade. (See clip below!)

Things may be far from over.

McGee’s most recent post on her Facbook reads: “In all seriousness, Im a big fan of Chelsea Lately…I was laughing my ass off…. feel so honored to have a transexual poke fun of me…”

OK! NEWS: CHELSEA HANDLER — “I ATTRACT NONSENSE IN MY LIFE”

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