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Joseph Gordon-Levitt and Seth Rogen team up to beat cancer in the upcoming film 50/50.

OK! GALLERY: SETH ROGEN HEADS TO JAPAN FOR THE PREMIERE OF THE GREEN HORNET

Joseph plays a 27-year-old who is diagnosed with cancer and told he has a 50/50 chance of beating it.

But it’s not all sad. It looks like Seth’s character helps to provide some comedic relief in the film.

The film also stars Anna Kendricks, Bryce Dallas Howard and Anjelica Huston.

OK! VIDEO: WATCH JOSEPH GORDON-LEVITT & NATALIE PORTMAN IN OFFICIAL HESHER TRAILER

Watch the trailer, below!

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