Kylie, 22, posted a video on her Instagram Stories where it looked like Travis, 28, blew smoke into her mouth in the backseat of a car as they left the afterparty.
The cosmetic billionaire seemed to "shotgun" the weed by inhaling the smoke after it was blown into her mouth and then exhaling.
The pair brought along 18-month-old daughter Stormi to the red carpet portion of the night.
Kylie and Travis showed massive PDA at the premiere and even had a few cute moments with Stormi.
The documentary chronicles the "Sicko Mode" singer on his rise to fame to fatherhood.
The film featured never-before-seen footage of the toddler's birth. The Kylie Skin founder showcased several clips of the doc on her Instagram Stories earlier this week where she called the birth the "best day of my life." Another clip showed Travis and Kylie attending an ultrasound appointment.
Do you think Kylie smoked weed at the party? Sound off in the comments below!