Marisa, 54, and Julianne, 58, appeared in an episode of "Finding your Roots" with Henry Louis Gates Jr.
The actresses, who've been friends since their college days, had matching DNA!
The show's host revealed the outcome while teasing the episode on Twitter. "Surprise! @MarisaTomei and @_JulianneMoore are long-lost cousins! We revealed to Marisa that she shares identical segments of DNA with her #CrazyStupidLove co-star (and friend since college!) on this week’s episode of #FindingYourRoots," he wrote.
The women couldn't contain their excitement about the discovery! "What an incredible gift to find out about my family’s roots with @HenryLouisGates! Eternally grateful for this generation and generations to come.... and the big surprise — discovering my friend is my REAL cousin! Hey cuz @juliannemoore," Marisa shared on Instagram.
What do you think of the actresses being related? Let us know in the comments.