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VIDEO: Sneak Peek at John Stamos' 'Glee' Debut

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Sept. 24 2010, Published 11:22 a.m. ET

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Tuesday's episode of Glee is going to be epic! Not only is Britney Spears appearing on the show for the all Britney episode, but John Stamos is making his Glee debut!

OK! GALLERY: MARK SALLING GETS A BIRDS EYE VIEW OF HOLLYWOOD

Glee cheerleader Brittany is taking on her biggest role yet in the "Britney/Brittany" episode on Tuesday, Sept. 28.

Entertainment Weekly has a sneak peek of Brittany (Heather Morris) busting out her Britney moves with the help of Santana (Naya Rivera). The girls visit Dr. John Stamos and demand some anesthesia and while they wait for the dosage, they nod off to Britney's "Me Against the Music."

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OK! NEWS: JAYMA MAYS ON JOHN STAMOS — "I'M A BIG FAN OF HIS"

Watch the clip below!

OK! GALLERY: GLEE KICKS OFF SEASON 2 IN STYLE AT HOLLYWOOD SOIREE

And if you didn't get enough of John in that clip, check out this clip from Celebuzz where John kisses Jayma Mays (Emma) right in front of Matthew Morrison (Mr. Schuester).

John appears on Glee along with Britney on Sept. 28!

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