From Jennifer Aniston To Sacha Baron, A Look Back At Ryan Seacrest's Most Monumental Red Carpet Interviews

After 14 years of hosting E!’s Live from the Red Carpet, Ryan Seacrest is finally ready to say goodbye to the glitz and glam of red carpet life... but we certainly aren't. The beloved host, 46, announced his bombshell departure in an Instagram post on Thursday, February 4. 

"I’ve decided to move on to new adventures," Seacrest shared in his statement. "I'll miss the whole crew that works so hard behind the scenes and of course my amazing partner Giuliana [Rancic]. Thanks to everyone for watching all these years."

From the Oscars to the Grammys and Golden Globes, Seacrest has been co-hosting the most A-list filled shows and interviewing sought-after celebrities since 2007. 

And while his time on the red carpet may be over, his entertaining interviews won't be forgotten.

Scroll through to see Seacrest's best red carpet moments. 

While dressed as his beloved character, Borat, Sacha Baron Cohen spilled ashes on Seacrest at the 2012 Oscars before he was taken away by security.

Four years after spilling ashes on Seacrest, Cohen hilariously crashed the host's interview with Lady Gaga at the 2016 Oscars.

Katy Perry candidly talked to Seacrest about "taking care of mental health" at the 2017 Grammys.

Kelly Clarkson comically reflected on when she fan-girled over Meryl Streep the first time she met her at the Golden Globes while talking to Seacrest at the 2018 Grammy Awards.

Jennifer Aniston jokingly threw shade at Seacrest at the 2020 Golden Globes after he purchased Ellen DeGeneres and wife Portia de Rossi's home, which she wanted.