Perhaps Cooper's most notable relationship was with model Irina Shayk, with whom he shares daughter Lea De Seine Shayk Cooper. The two were together from 2015 until they called it quits in 2019.
Following his divorce, Cooper and Renée Zellweger dated for nearly two years. "Can't say enough about her. I never met her before this movie, but I just love her. I love coming to work. I love acting with her. I can learn so much from her," Cooper said about the actress after starring in 2006's Case 39.
One of his longer relationships, the American Sniper actor dated Zoe Saldana from 2011 until 2013. "Zoe had planned to spend the holidays with Bradley and his family in Europe. They all were going to Paris, but things didn't work out between them. Zoe spent New Year's Eve with friends in Miami," an insider revealed at the time.
Although they both have denied it, while the two were promoting their hit film A Star Is Born, the the director and Lady Gaga got the rumor mill into a tizzy with their sizzling chemistry. "Just from a personal standpoint, it reduces the anxiety level," Cooper said of their connection while making the film.