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Christina Applegate's Rep Addresses Report of Hospitalization in L.A. Amid MS Diagnosis

christina applegate hospitalized la ms battle report
Source: MEGA

Christina Applegate's team reacted to a report claiming she's hospitalized in L.A. amid her multiple sclerosis battle.

April 17 2026, Published 7:21 a.m. ET

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Christina Applegate's team is speaking out after reports claim she's been in the hospital for a month.

“I have no comment on whether she is in the hospital or what her medical treatments are. She’s had a long history of complicated medical conditions that she has been refreshingly open about, as evidenced in her memoir and on her podcast," her rep said in a statement.

On Thursday, April 16, a news outlet reported that the 54-year-old actress has been in a hospital in Los Angeles since late March. She has been living with multiple sclerosis since her diagnosis in June 2021.

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image of Christina Applegate has been open about her multiple sclerosis diagnosis since 2021.
Source: MEGA

Christina Applegate has been open about her multiple sclerosis diagnosis since 2021.

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Over the past few years, Applegate has been open about what life with MS really looks like behind the scenes.

While she’s learned to cope, she’s also been honest about how difficult it’s been.

"I’m still sitting here like, ‘Boohoo, woe is me.’ I’m still mad about it," she said during a June 2024 episode of her podcast “MeSsy,” which she cohosts with Jamie-Lynn Sigler, who has also lived with MS for over two decades.

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image of The retired actress previously shared how difficult living with MS can be.
Source: MEGA

The retired actress previously shared how difficult living with MS can be.

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In her 2026 memoir, You With the Sad Eyes, published on March 3, the actress shared more about the early symptoms that began affecting her daily life.

"When I wake up, I often can’t get my arm to move far enough to grab the cup of water by my bed or my phone from its charger," she wrote.

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She also revealed that her condition is often triggered by infections and unpredictable symptoms.

"I start vomiting, almost like my body is trying to stop the noise, too," she wrote. "Then I end up in the hospital again. I just want everything to stop. But it won’t stop."

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image of Christina Applegate revealed more details about her condition in her book.
Source: MEGA

Christina Applegate revealed more details about her condition in her book.

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“For three years since I was diagnosed, I’ve been in the hospital upwards of 30 times,” Applegate said on her podcast. “That is unimaginable, OK? They’ve done every test known to man on me, put so much radiation into my body from CT scans to everything else.”

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image of The star's memoir was released on March 3.
Source: MEGA

The star's memoir was released on March 3.

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During a March 2024 appearance on “Armchair Expert” with Dax Shepard and Monica Padman, she opened up about the physical toll the disease has taken.

"(There are) sores all over my brain. My biggest one is behind my right eye, so my right eye hurts a lot," she said, noting that her vision is not currently affected.

"I'm not happy about the ones in my brain," Applegate added, explaining that lesions can also appear in other areas of the body, including the spine.

She also shared that she deals with mobility issues, saying her “hands go weird,” and that she sometimes experiences a “seizure-y” feeling in her brain.

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