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Rob Lowe Fires Back After Hollywood Tour Guide Mistakes Him for John Stamos: 'What the F---?'

photo of Rob Lowe and John Stamos
Source: mega

Rob Lowe and John Stamos are both 61 years old.

April 18 2025, Published 1:15 p.m. ET

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Rob Lowe was strolling through Hollywood when a tour guide referred to him as Full House actor John Stamos. However, fans of the Parks and Recreation star were quick to correct the mistake, as they knew exactly who he was.

In a post shared to Lowe’s Instagram this week, he could be seen approaching the tour bus. “This is John Stamos. Well, he looks like [John Stamos],” the tour guide announced on his loudspeaker.

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Source: @roblowe/Instagram

The '9-1-1' actor was quick to correct the driver for his mistake.

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Taken aback, the actor mouthed to the camera, “What the f---?”

As fans on the bus began to laugh, Lowe asked them, “Who am I?” To which they shouted, “Rob Lowe!”

The actor directed his attention to the driver, saying, “You gotta get better at your job!”

However, the guide admitted the mishap was due to the unlikely nature of seeing a true Hollywood star during his outing. “It’s about having fun, you know? I don’t expect to run into people, so… but thank you for your cool energy, man,” he said.

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rob lowe fires back at hollywood guide mistakes john stamos
Source: mega

Rob Lowe fired back at the driver for not knowing his name.

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Though Lowe laughed off the encounter, he captioned his Instagram post, “Am I being punk’d?” Nearly 2,000 fans of the 9-1-1 actor flooded his comments section by agreeing, “There is only one Rob Lowe.”

Many others, though, questioned if the driver was sober. Some even thought his "embarrassing" mistake was reason for him to be “fired immediately.”

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rob lowe fires hollywood tour guide mistakes john stamos
Source: mega

Some fans of Rob Lowe's suggested the tour guide wasn't sober, resulting in the mishap.

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“How many blunts did that tour guide smoke along the way?” pondered one.

“Guide sounds [totally] stoned,” wrote another.

Another Hollywood tour company stepped into the chat as well, saying, “Some of these other tour companies need to get it together! We would never!”

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rob lowe fires back hollywood tour guide mistakes him for john stamos
Source: mega

Fans were shocked that the two actors were mistaken for each other.

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Some fans of the 61-year-old praised him for looking better than Stamos, also 61. “John is good-looking, but he's no Rob Lowe!” exclaimed one. “How do you mistake Rob Lowe for John Stamos???? Get better glasses, dude… WOW,” agreed another.

Though Lowe and Stamos have no familial relation, the joke about their similar appearance has been long-standing. In March 2024, the Outsiders actor celebrated his 60th birthday, and his son John Owens, 29, posted a tribute on Instagram to honor his dad.

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rob lowe fires back at hollywood tour guide mistakes john stamos
Source: mega

Rob Lowe's son John Owens has joked in the past about his dad looking like John Stamos.

However, Owens photoshopped Stamos into the photo as a stand-in for his father. “If you could all be so kind, please send some birthday love my Dad’s way… HE’S SIXTY TODAY!!!! Love you forever, pops,” he captioned his post.

Lowe responded to his cheeky son, writing, “To say I’m surprised would be a lie.”

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