HEALTHChrissy Metz Started GLP-1 Medication After '5 or 6 Years' of Skepticism About the Weight-Loss Drug: 'I Thought It Wouldn't Work for Me'

Chrissy Metz confessed she was 'skeptical' of weight loss medication.
Aug. 10 2026, Published 4:15 p.m. ET
Chrissy Metz admitted she was "skeptical" for years before finally getting on GLP-1 medication.
The actress, 45, revealed on August 10 that she had finally taken the plunge and began the latest Hollywood weight loss craze after struggling with her health for decades.
She has been open about her weight loss challenges since she stepped into the spotlight on This Is Us, but admitted that she was apprehensive about jumping into the GLP-1 trend.
“I’m just not a girl who just wants to do something because some of my friends are doing it,” she told TODAY.com.

Chrissy Metz didn't think GLP-1s would work for her.
Metz confessed it was "five or six years" before she was willing to take the plunge, after noticing that the medication may be able to help with obesity-related complications she had seen her father deal with before he passed away.
"I’m not getting any younger,” she told People. “I’m in perimenopause, and there were obesity issues within my family and with my father, and I felt like I’ve tried so many modalities, whether it was diets or therapy, and none of it really worked for me."
She explained that many of the benefits of the weight loss medication were things she did not even consider.
"I’ve enjoyed the benefits that I didn’t think would come, because I was very skeptical," she added. "I was like, ‘I’m not taking this medication. I don’t wanna do this. It’s not gonna work for me.’ You know, all the things. But when I realized food noise was really a thing, that consumed a lot of my headspace, I was like, ‘Oh.’"
'I Vilified Food for So Long'

Chrissy Metz revealed GLP-1s silenced her 'food noise.'
The Hunting Wives actress admitted that one of the biggest benefits she has found since beginning the injection was a stop to the constant "food noise" in her head.
According to Harvard Health, the term refers to "persistent thoughts about food that a person perceives as unwanted or distressing."
Metz admitted she has struggled with "obsessive thoughts about food" for her entire life.
"It’s so nice not to be obsessing about what I’m going to have every minute," she explained. "Even as I’m still consuming the meal. I just vilified food for so long because I was taught that it was bad, and you shouldn’t eat this or that."
- Oprah Winfrey Slammed for Claiming 'Thin People' Aren't Thinking About Food After Taking Weight-Loss Drug: 'This Just Makes Me Mad'
- Kendra Wilkinson Rips Celebrities Who Aren't Truthful About GLP-1 Weight Loss: 'At Least I'm Honest'
- Oprah Winfrey Was 'Embarrassed' and 'Disappointed' by Her 'Overweight Body' Before Using GLP-1 Drugs: 'I Felt It Was My Fault'
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Chrissy Metz said her lab work has already improved.
Letting go of her preconceptions about weight loss medication allowed Metz to "put herself first," and she is already seeing the change in her lab work.
"My thinking was, how can I better myself and put myself first, which has always been the bane of my existence because I’m a people pleaser," she recalled. "But I know that my blood work is already better, and I’m headed in the right direction of getting ahead of things that needed getting ahead of."
Metz has combined the medication with exercise and a healthy diet, along with eight shows a week as she stars in & Juliet on Broadway.
"I know it’s not a magic wand, and I need to change other things, so I’ve been working with a trainer, and I’m lifting and putting on muscle, and it’s really about how comfortable I am, and learning what I’m capable of, so I really try not to have a number," she clarified. "I just want to feel strong and not have my morning ruined because I stepped on a scale and I’m several pounds above what I think I should be."
'Do What's Right for You'

Chrissy Metz encouraged people to be 'skeptical.'
Metz encouraged other prospective users to remain "skeptical" about what they choose to consume, regardless of how much she sings the medication's praises.
"Nothing is for everybody, and I think it’s important to be skeptical about anything we consume, put in our bodies, watch, listen to," she added.
The actress announced a partnership with Ro, which delivers GLP-1 medications to the patient's doorstep, and admitted that she knew the public would have opinions on her health from the moment it was revealed.
"No matter what I do, people are going to talk, but nobody’s in my body every day. Nobody is in my life every day. Nobody’s gone through the trauma I’ve gone through,” she said, later noting. "Do what’s right for you and your own health."


