"My hope is that, when I think about what they're going through, I think about the importance of family and I just pray that there is forgiveness and there is clarity and love and resolve at some point in time," the former first lady said. "Because there's nothing more important than family."
The 57-year-old is not the only public figure to remark on the two-hour interview.
"Obviously many of us caught the interview, as many Americans did and many people around the world," President Joe Biden’s press secretary Jen Psaki commented. "For anyone to come forward and speak about their own struggles with mental health and tell their own personal story, that takes courage."
Harry has been friendly with both Barack Obama and Biden. In fact, as OK! previously reported, it seems that Harry has a better bromance with the current President of the United States than his own sibling, Prince William.
The Sussexes told Oprah that one of the main reasons they decided to step down as senior royals last year was due to a "lack of support."
"We never left the family, and we only wanted to have the same type of role that exists. There's senior members and there's non-senior. We said specifically, senior roles," Meghan told Oprah. "[There are people] who earn a living, live on palace grounds, can support the Queen if and when called upon. We weren't reinventing the wheel."
The couple was said to be "in a lot of pain," but the Palace allegedly did not provide them "with the help that they needed."
The Duchess said her mental health suffered greatly, largely due to the British press, and had "very clear suicidal thoughts."
“Look, I was really ashamed to say it at the time and ashamed to have to admit it to Harry, especially, because I knew how much loss he suffered," Meghan admitted. "I just didn’t want to be alive anymore, and that was a very clear and real and frightening constant thought. And I remember how he just cradled me."
There were also allegedly "conversations" about what color skin Archie would have when he was born as well as his title within the family.
"The idea of our son not being safe and the idea of the first member of color in this family not being titled in the same way that other grandchildren would be..." Meghan said. "It’s not their right to take it away, and so I think even with that convention, they want to change the convention for Archie. Well, why?"
However, Queen Elizabeth II and Prince Philip were not involved in those conversations about Archie's skin, Oprah later confirmed. Meghan added that she enjoyed being in the Queen’s company and that she "has always been wonderful to me," adding: "She's always been warm, welcoming, and inviting."
"The issues raised, particularly that of race, are concerning. While some recollections may vary, they are taken very seriously and will be addressed by the family privately," Buckingham Palace responded to the interview in a statement. "Harry, Meghan and Archie will always be much loved family members."
Access Hollywood was the first to report on Michelle Obama's thoughts on Meghan and Harry's interview.