One week after Harry and Meghan's bombshell interview with Oprah Winfrey — discussing their royal life behind the scenes and Meghan's tumultuous relationship with her half-sister and estranged father, Thomas Markle — Samantha said that she sees Harry and Meghan's relationship "ending in divorce unless they get extensive counseling and can agree to work on being honest and work on apologies to everyone they’ve damaged in the course of this."
“None of this has been honest and the damage to the Royals has been massive," she added while speculating that Harry may already be pulling away from his wife, whom Samantha accuses of nonstop lying.
Harry has "got to have a sense of, 'Oh my God, everything you said to me has been a lie,'" she said to TMZ of Harry's thoughts on the Suits alum.
Click here to watch the clip of Samantha speculating about the couple's marriage.
Samantha also said Meghan would need to issue a public apology to their father, Thomas, in order to restore their relationship following their 2018 fallout. As OK! previously reported, Meghan, 39, and her estranged father, 76, haven't spoken since he staged paparazzi photos ahead of the Sussex's 2018 wedding.
As Meghan explained during the couple's CBS tell-all on Sunday, March 7, she and Harry offered Thomas multiple chances to come clean about the photos, but "he wasn't able to do that."
"I look at Archie, I think about this child [on the way], and I genuinely can't imagine doing anything to intentionally cause pain to my child. I can't imagine it. So it's hard for me to reconcile that," Meghan candidly told Oprah.
Samantha's thoughts on the couple's marriage, which she claimed is doomed, come after Meghan shared her opinion on Samantha's book, The Diary of Princess Pushy’s Sister, which was released in January. “I think it would be very hard to 'tell all' when you don’t know me,” Meghan said during the primetime interview.
"I don’t feel comfortable talking about people that I really don’t know," she added. "I grew up as an only child, which everyone who grew up around me knows, and I wished I had siblings."
Samantha has since refuted Meghan's memory of their childhood while speaking with Inside Edition on Monday, March 8. "I don’t know how she can say, 'I don’t know her' and she was an only child," Samantha said. "We’ve got photographs over a lifespan of us together. So how can she not know me?"
She also responded to the revelations Meghan made regarding her mental health while she was a senior royal member.
During her sit down with Oprah, Meghan revealed she had “very clear and very scary” suicidal thoughts and "didn't want to be alive anymore" because she "didn’t see a solution" on how to endure the pressure of royal life.
"Depression is not an excuse for treating people like dishrags and disposing of them," Samantha, 56, said of Meghan's tumultuous time in the spotlight.
Samantha and Meghan have been at odds with each other since before the actress wed Harry, due to the fact that Samantha — who was not invited to the royal wedding — dragged Meghan in the press and on social media.
Earlier this week, Samantha trashed her younger half-sister once more, accusing her of suffering from "narcissistic personality disorder." She even went so far as to equate the prince to a kidnapping victim who fell in love with his captor.